Prozac is an antidepressant of selective serotonin reuptake inhibitors (SSIR) class. It is used to treat depression and obsessive-compulsive disorder in adults. When gabapentin is taken with Prozac, no direct contradiction occurred. Prozac in general reduced or antagonized the anticonvulsant effects of antiepileptic drug such as gabapentin. Prozac also decreased neuropathic pain effect. These drugs showed mild to moderate interaction. The above discussed interaction is not significant. But if side effect symptoms increase, a person should consult with their physician or chemist. One should not start or stop their drugs by themselves, as this may cause increased seizures which could prove to be fatal.