Gabapentin and tylenol extra strength or PM, drug interaction
Tylenol is an acetaminophen which is used to relieve pain and fever in many conditions such as headache, muscle ache etc. A comparative study was done to evaluate the effects of premedication protection with Tylenol, gabapentin and combination of gabapentin and Tylenol on post-operative analgesia in patients undergoing open cholecystectomy under general anaesthesia. Four groups were divided: 1. Placebo, 2. Tylenol, 3. Gabapentin, and 4. Gabapentin and Tylenol. The drugs were given two hours prior to surgery. Visual analogue scale pain intensity scores (VASPI) were recorded along with side effects like episodes of nausea, vomiting, higher levels of pain. Outcomes from the study showed that gabapentin with tylenol helps to lessen postoperative pain scores with less episodes of nausea than gabapentin and tylenol alone.